The course sheds light on the complex interactions between international and domestic law, global health and human rights, with particular emphasis on their interactions in addressing public health challenges. With a focus on strengthening the ability of lawyers to engage in multi-disciplinary work, the course brings law students together with public health and doctoral students in other USC programs to engage in real life problem solving. The course provides the basis for literacy in international human rights law, including core principles, key documents, institutions, governance and practices relevant to global health work, all with the aim of strengthening the practice aspects of legal work in doing this work in the United States, in other countries, and with the United Nations. Frameworks for analyzing and addressing the interactions between law, health and human rights are introduced and applied, including the effects of law on health. Topics such as sexuality, reproductive health, HIV/AIDS, the Zika virus, and non- communicable disease will be used to illustrate and explore practical applications of law and human rights to pressing global health challenges.